Fatigue is a common symptom. Almost everyone feels it during short-term illness. Fortunately, fatigue usually goes away when the illness is over.

But sometimes fatigue doesn’t go away. It doesn’t get better with rest. And the cause might be unclear.

Fatigue reduces energy, the ability to do things and the ability to focus. Ongoing fatigue affects quality of life and state of mind.

Most of the time fatigue can be traced to one or more lifestyle issues, such as poor sleep habits or lack of exercise. Fatigue can be caused by a medicine or linked to depression. Sometimes fatigue is a symptom of an illness that needs treatment.

Lifestyle factors

Fatigue may be related to:

Conditions

Exhaustion that doesn’t let up might be a sign of:

Call 911 or your local emergency number

Get emergency help if you have fatigue and any of the following:

Seek help for urgent mental health problems

Get emergency help if your fatigue is related to a mental health problem and your symptoms also include thoughts of harming yourself or of suicide. Call 911 or your local emergency services number right away. Or contact a suicide hotline. In the U.S., call or text 988 to reach the 988 Suicide & Crisis Lifeline. Or use the Lifeline Chat.

Schedule a doctor’s visit

Call for an appointment with a health care provider if resting, reducing stress, eating well and drinking plenty of fluids for two or more weeks hasn’t helped your fatigue.

© 1998-2024 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.

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