Splenectomy is surgery to remove the spleen. The spleen is an organ that sits under the rib cage on the upper left side of the belly. It helps fight infection and filters material the body doesn’t need, such as old or damaged blood cells, from the blood.

The most common reason for splenectomy is to treat a spleen that tears, called a ruptured spleen. A belly injury often is the cause of the tear.

Splenectomy also treats other conditions. Conditions may include an enlarged spleen that is causing discomfort, called splenomegaly. Other conditions include some blood conditions, certain cancers, infection, and cysts or tumors that aren’t cancer.

Surgeons most often do splenectomies using a tiny video camera and special surgical tools. This is called laparoscopic splenectomy. People who have this type of surgery may be able to leave the hospital the same day and recover fully in two weeks.

Splenectomy may treat many conditions. Your healthcare professional may suggest splenectomy if you have one of the following:

A healthcare professional also may remove a spleen to help diagnose a condition. This might happen if a spleen is too large without a known cause.

Splenectomy most often is safe. But as with any surgery, splenectomy may cause complications, including:

Long-term risk of infection

People who have their spleens removed are more likely to get serious or life-threatening infections. They may need vaccines for pneumonia, Haemophilus influenzae type b, also called Hib, and meningococci. And they may need to take antibiotics to prevent infections.

Food and medications

Before your procedure, you may need to stop taking certain medicines and supplements for a time. You also may need to not eat or drink for a time. A member of your healthcare team tells you how to prepare.

Other precautions

If you have time before the surgery, you may need to get blood transfusions. This is to make sure that you have enough blood cells after your spleen is removed.

Your healthcare team also may ask that you get a pneumococcal vaccine and possibly other vaccines to help prevent infection after your spleen is removed.

Before the procedure

Right before your surgery, you get a medicine to put you in a sleeplike state, called a general anesthetic. A healthcare professional called an anesthesiologist or an anesthetist gives you the medicine as a gas to breathe through a mask or as a liquid that goes into a vein.

The surgical team puts heart monitor leads on your chest and a blood pressure cuff on your arm. That way the team can watch your heart rate, blood pressure and blood oxygen throughout the procedure.

During the procedure

Your surgeon does the surgery using either a minimally invasive, called laparoscopic, or an open procedure. The method used often depends on the size of the spleen. The larger the spleen, the more likely your surgeon does an open splenectomy.

After the procedure

If you had splenectomy because your spleen tore, you don’t need more treatment. If you had it to treat another condition, you may need more treatment.

Life without a spleen

After splenectomy, other organs in the body take over most of the work of the spleen. People without a spleen can be active. But they’re at a higher risk of getting sick or getting serious infections. This risk is highest shortly after surgery. People without a spleen also may have a harder time getting better after an illness or injury.

To lower your risk of infection, your healthcare team may ask you to get vaccines. Besides an annual flu shot, you may need to be vaccinated for pneumonia, Haemophilus influenzae type b, also called Hib, and meningococci.

You also may take antibiotics to prevent illness. Antibiotics are mainly for children under 5 and people who have other conditions that raise the risk of serious infections.

After splenectomy, call your healthcare professional at the first sign of an infection, such as:

Make sure anyone caring for you knows that you’ve had your spleen removed. You might wear a medical alert bracelet that tells others that you don’t have a spleen.

© 1998-2024 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.

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