{"id":52791,"date":"2025-04-25T22:08:38","date_gmt":"2025-04-26T02:08:38","guid":{"rendered":"https:\/\/www.hancockhealth.org\/mayo-health-library\/neutropenia-low-neutrophil-count\/"},"modified":"2026-02-04T12:12:09","modified_gmt":"2026-02-04T17:12:09","slug":"neutropenia-low-neutrophil-count","status":"publish","type":"mayo","link":"https:\/\/www.hancockhealth.org\/ja\/mayo-health-library\/neutropenia-low-neutrophil-count\/","title":{"rendered":"Neutropenia (low neutrophil count)"},"content":{"rendered":"<div class=\"container mx-auto   wordpress-block wordpress- core-\">\n<p>Neutropenia (noo-troe-PEE-nee-uh) means that the body has too few neutrophils, a type of white blood cells. All white blood cells help the body fight infections. But neutrophils are important for fighting certain infections, especially those caused by bacteria.<\/p>\n<p>If you have neutropenia, you likely won&#8217;t know it based on any symptoms. People often find out that they have neutropenia when they&#8217;ve had blood tests done for other reasons.<\/p>\n<p>A single blood test showing low levels of neutrophils doesn&#8217;t mean you have neutropenia for sure. These levels can vary from day to day. So if a blood test shows that you have low levels, the test needs to be repeated. The repeated test may confirm whether you have neutropenia.<\/p>\n<p>Neutropenia can raise your risk of infections. When neutrophil levels are very low, even the common bacteria from the mouth and digestive tract can cause serious illness.<\/p>\n<p>Various health conditions and treatments can cause neutropenia. Depending on the cause, neutropenia happens because neutrophils are destroyed, made in fewer numbers or stored in an irregular way.<\/p>\n<p>Causes of neutropenia include the following:<\/p>\n<h3>Cancer and cancer treatments<\/h3>\n<p>Certain cancers can cause neutropenia. These include:<\/p>\n<ul>\n<li>Leukemia <\/li>\n<li>Lymphoma <\/li>\n<li>Multiple myeloma <\/li>\n<\/ul>\n<p>Various cancer treatments also can cause neutropenia. For instance, chemotherapy and radiation can destroy neutrophils and other healthy cells along with cancer cells.<\/p>\n<ul>\n<li>Bone marrow transplant <\/li>\n<li>\u5316\u5b66\u7642\u6cd5 <\/li>\n<li>Radiation therapy <\/li>\n<li>Targeted therapy.<\/li>\n<\/ul>\n<h3>Medicines<\/h3>\n<ul>\n<li>Medicines to treat overactive thyroid such as methimazole and propylthiouracil.<\/li>\n<li>Antibiotics such as nafcillin, penicillin G and oxacillin.<\/li>\n<li>Antiviral medicines such as acyclovir (Sitavig, Zovirax), ganciclovir (Ganzyk-RTU, Valcyte, others) and oseltamivir (Tamiflu).<\/li>\n<li>Anti-inflammatory medicines for conditions such as ulcerative colitis or rheumatoid arthritis. These include sulfasalazine (Azulfidine), leflunomide (Arava) and methotrexate (Rasuvo, Trexall, others).<\/li>\n<li>Antipsychotic medicines such as clozapine (Clozaril, Versacloz) and chlorpromazine.<\/li>\n<li>Medicines to treat irregular heart rhythms, including quinidine and procainamide.<\/li>\n<li>Medicines to treat some skin conditions, including dapsone (Aczone) and isotretinoin (Absorica, Amnesteem, others).<\/li>\n<li>A veterinary drug called levamisole that&#8217;s not approved for human use in the United States but may be mixed in with cocaine.<\/li>\n<\/ul>\n<h3>Infections<\/h3>\n<ul>\n<li>Chickenpox <\/li>\n<li>Coronavirus disease 2019 (COVID-19) <\/li>\n<li>Cytomegalovirus (CMV) infection <\/li>\n<li>Epstein-Barr virus<\/li>\n<li>A\u578b\u809d\u708e <\/li>\n<li>B\u578b\u809d\u708e <\/li>\n<li>C\u578b\u809d\u708e <\/li>\n<li>HIV\/AIDS <\/li>\n<li>\u9ebb\u75b9 <\/li>\n<li>Rubella <\/li>\n<li>Salmonella infection <\/li>\n<li>Sepsis (an overwhelming bloodstream infection)<\/li>\n<\/ul>\n<h3>Autoimmune diseases<\/h3>\n<ul>\n<li>Granulomatosis with polyangiitis <\/li>\n<li>Lupus <\/li>\n<li>Rheumatoid arthritis <\/li>\n<\/ul>\n<h3>Bone marrow disorders<\/h3>\n<ul>\n<li>Aplastic anemia <\/li>\n<li>Myelodysplastic syndromes <\/li>\n<li>Myelofibrosis <\/li>\n<\/ul>\n<h3>Other causes<\/h3>\n<ul>\n<li>Genetic conditions such as Fanconi anemia, Kostmann syndrome and Shwachman-Diamond syndrome.<\/li>\n<li>Unknown reasons called chronic idiopathic neutropenia.<\/li>\n<li>Low levels of nutrients such as vitamin B-12, copper or folate.<\/li>\n<li>Some conditions of the spleen.<\/li>\n<\/ul>\n<p>People can have neutropenia without a higher risk of infection. This is known as benign neutropenia.<\/p>\n<p>Neutropenia doesn&#8217;t cause obvious symptoms. So it alone likely won&#8217;t prompt you to get a healthcare checkup. Most often, blood tests that are done for other reasons find neutropenia.<\/p>\n<p>Talk with your healthcare professional about what your test results mean. You&#8217;ll need more than one blood test to confirm that you have neutropenia. You also may need more tests to find out what&#8217;s causing your neutropenia. A finding of neutropenia combined with the results from other tests might pinpoint the cause.<\/p>\n<p>If you have neutropenia or take medicines that can cause neutropenia, call your healthcare professional right away if you notice symptoms of an infection. Infection symptoms can include:<\/p>\n<ul>\n<li>Fever above 100.4 degrees Fahrenheit (38 degrees Celsius).<\/li>\n<li>Chills and sweats.<\/li>\n<li>A new cough or a cough that becomes worse.<\/li>\n<li>Shortness of breath.<\/li>\n<li>A stuffy nose.<\/li>\n<li>A sore throat or a new mouth sore.<\/li>\n<\/ul>\n<p>Some other possible symptoms of an infection are:<\/p>\n<ul>\n<li>Burning or pain with urination.<\/li>\n<li>A stiff neck.<\/li>\n<li>Diarrhea or vomiting.<\/li>\n<li>A change in skin color or swelling around any area where skin is broken or cut.<\/li>\n<li>Unusual vaginal discharge.<\/li>\n<li>New pain, including in the stomach area or rectum.<\/li>\n<\/ul>\n<p>If you have neutropenia, you can take steps to lower your risk of infections. These safety measures include the following:<\/p>\n<ul>\n<li>Stay up to date on vaccinations, such as those for the flu and COVID-19.<\/li>\n<li>Wash your hands often.<\/li>\n<li>Wear a face mask in crowded places or around people who are sick.<\/li>\n<li>Try not to have close contact with people who are sick.<\/li>\n<li>Cook meat and eggs thoroughly to kill any germs.<\/li>\n<li>Wash raw fruits and vegetables well.<\/li>\n<li>Don&#8217;t share food, drink cups, utensils or toothbrushes.<\/li>\n<\/ul>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Learn what can cause a lack of certain white blood cells.<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","tags":[1686,1685,1682],"class_list":["post-52791","mayo","type-mayo","status-publish","hentry","tag-anatomical-structure","tag-condition","tag-person-group-concept","content_type-symptoms"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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