{"id":52683,"date":"2025-04-25T22:04:03","date_gmt":"2025-04-26T02:04:03","guid":{"rendered":"https:\/\/www.hancockhealth.org\/mayo-health-library\/tianeptine-is-safe-use-possible\/"},"modified":"2026-02-04T12:07:15","modified_gmt":"2026-02-04T17:07:15","slug":"tianeptine-is-safe-use-possible","status":"publish","type":"mayo","link":"https:\/\/www.hancockhealth.org\/es\/mayo-health-library\/tianeptine-is-safe-use-possible\/","title":{"rendered":"Tianeptine: Is safe use possible?"},"content":{"rendered":"
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Tianeptine is a medicine available for use in some European, Asian and South American countries to treat anxiety, depression and irritable bowel syndrome. In other countries, including the U.S., tianeptine is not approved for any medical use.<\/p>\n

Although tianeptine is not approved in the U.S., it can be bought online and at small stores. It may be sold under names such as ZaZa or Tianna Red. Tianeptine may be referred to as “gas station heroin.” In some places it is labeled as a dietary supplement that enhances cognition and stabilizes mood. Tianeptine also may be labeled to help with pain, decrease appetite and increase sexual performance.<\/p>\n

When taken in small doses, tianeptine may help with symptoms of anxiety, depression and irritable bowel syndrome. However, misuse can lead to taking larger doses and dependence. When taken at higher doses, tianeptine can cause a high or a feeling of euphoria. Taking high doses of tianeptine can be fatal.<\/p>\n

Some people take tianeptine with opioids, alcohol or other drugs to heighten the effects. Mixing these substances may lead to increased heart rate, lowered blood pressure, seizures and cardiac arrest. Tianeptine is sometimes misused to self-treat withdrawal symptoms from alcohol and other substances. People with a history of substance misuse are at a higher risk of misusing tianeptine. <\/p>\n

Tianeptine can have side effects, even when taken at lower doses. These may include:<\/p>\n